| 1990 | West Virginia High Technology Consortium founded by Congressman Alan B. Mollohan |
| 1992 | Consortium reaches 50 company members |
| 1993 | West Virginia High Technology Consortium Foundation established |
| 1993 | NASA IV & V Facility opens |
| 1995 | Consortium reaches 100 company members |
| 1995 | FBI facility opens in Clarksburg |
| 1996 | Alan B. Mollohan Innovation Center opens |
| 1996 | WVHTC and WVHTC Foundation merge |
| 1999 | Congressman Alan B. Mollohan establishes Decadal Review Committee |
| 2000 | WVHTC Foundation begins reorganization |
| 2000 | National Energy Technology Laboratory named national lab |
| 2001 | National White Collar Crime Center/Internet Fraud Complaint Center moves into Technology Park |
| 2001 | Biometrics Fusion Center contract awarded |
| 2001 | Decadal Review Committee releases report |
| 2001 | ISR facility breaks ground |
| 2002 | I-79 Park expands with purchase of more than 400 acres |
| 2002 | VC Link system sold to North Carolina |
| 2002 | Affiliate Leadership Council established |
| 2002 | INNOVA commercialization program launched |
| 2003 | WVHTC Foundation awarded state grant for I-79 park expansion |
| 2004 | WVHTC Foundation establishes Intellectual Property Management Group and expanded to Wheeling |
| 2004 | Global Grid Exchange launched |
| 2005 | WVHTC Foundation establishes Public Safety and Homeland Security Group and expands to Moundsville |
| 2005 | WVHTC Foundation expands I-79 Technology Park by breaking ground on 125,000 square-foot building |